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LC/MS
A Perkin-Elmer Sciex API 300 triple quadrupole mass spectrometer
coupled to a Shimadzu gradient LC system and a temperature controlled autosampler;
this LC/MS system is capable of performing electrospray (ESI) and
atmospheric pressure ionization (API), positive and negative ion
detection, single ion and multiple reaction monitor, and collision
induced dissociation experiments. Additionally, this system is equipped
with a capillary LC/MS interface, and can be connected online with UV
and photodiode-array detection.
A Finnigan LCQ Ion Trap LC/MS coupled to a Shimadzu gradient LC system
and a temperature controlled autosampler; this LC/MS system is capable
of performing electrospray (ESI) and atmospheric pressure ionization
(API), positive and negative ion detection, single ion and multiple ion
detection, and collision induced dissociation experiments. This
instrument can perform (MS)n experiment which is essential for
structural identification.
Additionally,
we have a Finnigan TSQ, quantum ultra EMR system available through The
Ohio State University Comprehensive Cancer Center Shared Resource
program.
OSUCCC Pharmacoanalytical
Shared Resource (PhASR)
Other related equipments
include several HPLC instruments with UV, fluorescence, and
electrochemical detectors and gas chromatographs.
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